Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.33 |
| ▸ | KDM6B | O15054 | 2/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.31 |
| ▸ | RAF1 | P04049 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | OXTR | P30559 | 1/20 | 0.30 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30989795 | 0.92 | LTB4R (0.34) | GPR6KDM4CKDM6BLTB4RLTB4R2 | |
| SCHEMBL30989839 | 0.91 | TRPM8 (0.37) | GPR6KDM4CKDM6BLTB4RLTB4R2 | |
| SCHEMBL30989859 | 0.89 | GPR6 (0.39) | GPR6KDM4CNTRK1HCRTR1HCRTR2 | |
| SCHEMBL30989838 | 0.89 | GPR6 (0.39) | GPR6KDM4CNTRK1HCRTR1HCRTR2 | |
| SCHEMBL30989796 | 0.86 | GPR6 (0.33) | GPR6 | |
| SCHEMBL30989805 | 0.81 | GPR6 (0.39) | GPR6NTRK1HCRTR2 | |
| SCHEMBL30989815 | 0.81 | TRPM8 (0.36) | HCRTR1HCRTR2 | |
| SCHEMBL30989774 | 0.80 | GPR6 (0.37) | GPR6KDM4CLTB4RLTB4R2HCRTR1 | |
| SCHEMBL30989950 | 0.80 | GPR6 (0.37) | GPR6KDM4CLTB4RLTB4R2HCRTR1 | |
| SCHEMBL30989834 | 0.79 | P2RX7 (0.37) | KDM4CLTB4RLTB4R2NTRK1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612131-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2025-09-10 | — | — | EP | claimed |
| WO-2024095003-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2024-05-10 | — | — | WO | claimed |
| EP-4612131-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024095003-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2024-05-10 | — | — | WO | disclosed |