Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31719401 | 0.81 | P2RY12 (0.44) | — | |
| SCHEMBL16722630 | 0.76 | PLAU (0.36) | PLAUALDH1A1MEN1KMT2A | |
| SCHEMBL4707750 | 0.76 | SLC22A12 (0.49) | HCAR2NAPRTTTRTSHRPLAU | |
| SCHEMBL18378990 | 0.73 | TDP1 (0.50) | ALDH1A1MEN1KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL3650691 | 0.72 | PLAU (0.47) | HCAR2NAPRTTTRTSHRPLAU | |
| SCHEMBL29365646 | 0.69 | HCAR2 (0.50) | HCAR2NAPRTTTRTSHRALDH1A1 | |
| SCHEMBL232290 | 0.69 | HCAR2 (0.50) | HCAR2NAPRTTTRTSHRALDH1A1 | |
| SCHEMBL3650453 | 0.68 | HCAR2 (0.48) | HCAR2NAPRTTTRTSHRPLAU | |
| Hydrochloric Acid SCHEMBL7476482 | 0.68 | HCAR2 (0.48) | HCAR2NAPRTTTRTSHRALDH1A1 | |
| SCHEMBL199221 | 0.68 | TTR (0.54) | HCAR2NAPRTTTRTSHRPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024140850-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | 苏州必扬医药科技有限公司 | 2024-07-04 | — | — | WO | disclosed |