Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 known ✓ | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 known ✓ | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 known ✓ | P35228 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | PLA2G2C | Q5R387 | 3/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28658463 | 0.96 | HSD17B10 (0.72) | HSD17B10TDP1MAPTUSP2KDM4E | |
| Propionic Acid SCHEMBL3286165 | 0.89 | HSD17B10 (0.75) | HSD17B10TDP1MAPTUSP2KDM4E | |
| SCHEMBL17164541 | 0.89 | — | — | |
| SCHEMBL34792 | 0.89 | — | — | |
| SCHEMBL21356623 | 0.89 | HSD17B10 (1.00) | HSD17B10TDP1MAPTUSP2KDM4E | |
| SCHEMBL9637969 | 0.89 | — | — | |
| Methacrylic Acid SCHEMBL26637849 | 0.88 | HSD17B10 (0.67) | HSD17B10TDP1MAPTUSP2KDM4E | |
| Acetic Acid Methyl Ester SCHEMBL28347932 | 0.88 | HSD17B10 (0.72) | HSD17B10TDP1MAPTUSP2KDM4E | |
| Acetic Acid SCHEMBL3249565 | 0.88 | HSD17B10 (0.59) | HSD17B10TDP1MAPTUSP2KDM4E | |
| SCHEMBL30725962 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110088072-A | Novel compound, semiconductor material, film using same, and method for manufacturing semiconductor | 默克专利有限公司 | 2019-08-02 | — | — | CN | claimed |
| US-20050026260-A1 | Enzymatic resolution of propylene glycol alkyl (or aryl) ethers and ether acetates | RESNICK SOL M (US) | 2005-02-03 | — | — | US | claimed |
| WO-2020138189-A1 | FILM FORMING COMPOSITION | 日産化学株式会社 | 2020-07-02 | — | — | WO | disclosed |
| WO-2020085508-A1 | FILM-FORMING COMPOSITION | 日産化学株式会社 | 2020-04-30 | — | — | WO | disclosed |
| CN-104834183-B | Thermosetting ink composition | 东友精细化工有限公司 | 2019-11-12 | — | — | CN | disclosed |
| CN-110139912-A | Optical medium and optical device | 默克专利股份有限公司 | 2019-08-16 | — | — | CN | disclosed |
| CN-110068988-A | Etch-resist resin composition, film, color conversion device and electronic equipment | 三星显示有限公司 | 2019-07-30 | — | — | CN | disclosed |
| CN-110018615-A | Green photonasty resin composition, colored filter and image display device | 东友精细化工有限公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-110007562-A | Photopolymerizable unsaturated-resin and photosensitive resin composition containing the photopolymerizable unsaturated-resin | 罗门哈斯电子材料韩国有限公司 | 2019-07-12 | — | — | CN | disclosed |
| CN-109983084-A | Composition containing nano-sized luminescent material | 默克专利股份有限公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-109810589-A | Light converts resin combination, light conversion layer folds substrate and image display device | 东友精细化工有限公司 | 2019-05-28 | — | — | CN | disclosed |
| EP-1490501-A2 | ENZYMATIC RESOLUTION OF PROPYLENE GLYCOL ALKYL (OR ARYL) ETHERS AND ETHER ACETATES | Dow Global Technologies Inc. (US) | 2004-12-29 | — | — | EP | disclosed |
| US-6824833-B2 | STACKED DIELECTRIC | JSR CORPORATION (JP) | 2004-11-30 | — | — | US | disclosed |
| US-6749944-B2 | VAPOR DEPOSITION, OSCILLATION, HEATING USING ORGANOSILICON COMPOUND; FORMING DIELECTRIC | JSR CORPORATION (JP) | 2004-06-15 | — | — | US | disclosed |
| WO-2003083126-A2 | ENZYMATIC RESOLUTION OF PROPYLENE GLYCOL ALKYL (OR ARYL) ETHERS AND ETHER ACETATES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-10-09 | — | — | WO | disclosed |
| US-20030077461-A1 | Stacked film, insulating film and substrate for semiconductor | JSR CORPORATION (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1298176-A2 | Stacked film insulating film and substrate for semiconductor | JSR Corporation (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-20030059628-A1 | Stacked film, method for the formation of stacked film, insulating film, and substrate for semiconductor | JSR CORPORATION (JP) | 2003-03-27 | — | — | US | disclosed |
| EP-1295924-A2 | Stacked film, method for the formation of stacked film, insulating film, and substrate for semiconductor | JSR Corporation (JP) | 2003-03-26 | — | — | EP | disclosed |
| CN-1091147-A | The polyester-based coating compositions having of high pigment/binder ratio | EXXON CHEMICAL PATENTS INC (US) | 1994-08-24 | — | — | CN | disclosed |