Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | CD38 | P28907 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20840381 | 1.00 | CYP1A2 (0.52) | CYP1A2LMNAKDM4EHTTSMN1; SMN2 | |
| SCHEMBL13283258 | 0.75 | LMNA (0.83) | CYP1A2LMNAKDM4EHTTSMN1; SMN2 | |
| SCHEMBL13283268 | 0.74 | LMNA (0.59) | CYP1A2LMNAKDM4EHTTSMN1; SMN2 | |
| SCHEMBL24686076 | 0.72 | LMNA (0.65) | CYP1A2LMNAKDM4EHTTSMN1; SMN2 | |
| SCHEMBL30991006 | 0.71 | HTT (0.64) | CYP1A2LMNAKDM4EHTTSMN1; SMN2 | |
| SCHEMBL20840393 | 0.71 | HTT (0.64) | CYP1A2LMNAKDM4EHTTSMN1; SMN2 | |
| SCHEMBL6364148 | 0.70 | ALDH1A1 (0.60) | LMNAKDM4ESMN1; SMN2MAPTKMT2A | |
| SCHEMBL8306177 | 0.70 | GRM1 (0.55) | EGFR | |
| SCHEMBL13990178 | 0.69 | CYP1A2 (1.00) | CYP1A2LMNAKDM4EHTTSMN1; SMN2 | |
| SCHEMBL20840498 | 0.69 | PRKCA (0.38) | CYP1A2KDM4EMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111247152-B | Cyclic iminopyrimidine derivatives as kinase inhibitors | 璧辰医药技术股份有限公司 | 2024-07-16 | — | — | CN | disclosed |