Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.30 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3095596 | 0.96 | CPB2 (0.36) | CYP1A2FPR2MEN1KMT2APPARD | |
| SCHEMBL3105822 | 0.88 | FOLH1 (0.37) | CYP1A2FPR2MEN1KMT2APPARD | |
| SCHEMBL3098098 | 0.86 | FPR2 (0.43) | FPR2PPARDTSHRCA12CA1 | |
| SCHEMBL3105775 | 0.86 | FPR2 (0.37) | CYP1A2FPR2MEN1KMT2APPARD | |
| SCHEMBL3100418 | 0.85 | PPARD (0.42) | FPR2PPARDTSHRCA12CA1 | |
| SCHEMBL3103384 | 0.85 | CA12 (0.39) | FPR2PPARDTSHRCA12CA1 | |
| SCHEMBL3098952 | 0.84 | FOLH1 (0.42) | CA12CA1CA2CA9CPB2 | |
| SCHEMBL3091598 | 0.84 | PLAU (0.34) | FPR2PPARDTSHRPLAU | |
| SCHEMBL3106298 | 0.84 | FPR2 (0.34) | FPR2KMT2APPARDTSHRPLAU | |
| SCHEMBL3106289 | 0.83 | CA12 (0.41) | FPR2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |