Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 8/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | GGT1 | P19440 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3105822 | 0.96 | FOLH1 (0.37) | FOLH1SLC6A5GSRTLR2CPB2 | |
| SCHEMBL3091681 | 0.89 | FPR2 (0.36) | FOLH1SLC6A5TLR2CPB2SIRT6 | |
| SCHEMBL3095596 | 0.89 | CPB2 (0.36) | FOLH1SLC6A5TLR2CPB2SIRT6 | |
| SCHEMBL3105775 | 0.84 | FPR2 (0.37) | FOLH1TLR2CPB2MMP9SIRT6 | |
| SCHEMBL3099111 | 0.84 | CYP1A2 (0.33) | CPB2SIRT6SIRT1CA12CA1 | |
| SCHEMBL3091646 | 0.84 | CA12 (0.40) | FOLH1TLR2SIRT6SIRT1CA12 | |
| SCHEMBL3098722 | 0.83 | FPR2 (0.43) | FOLH1CA12CA1CA2CA9 | |
| SCHEMBL3097853 | 0.82 | C3AR1 (0.43) | FOLH1CA12CA1CA2CA9 | |
| SCHEMBL3091741 | 0.82 | PPARD (0.43) | CA12CA1CA2CA9 | |
| SCHEMBL3103245 | 0.82 | CA12 (0.38) | FOLH1TLR2SIRT6SIRT1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |