Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 4/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | CCR4 | P51679 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23620165 | 1.00 | NR4A2 (0.42) | NR4A2MEN1KMT2ATSHRNPC1 | |
| SCHEMBL23620321 | 0.90 | PRKAG1 (0.42) | NR4A2MEN1KMT2ATSHRNPC1 | |
| SCHEMBL30991309 | 0.90 | PRKAG1 (0.42) | NR4A2MEN1KMT2ATSHRNPC1 | |
| SCHEMBL23610290 | 0.83 | MEN1 (0.37) | NR4A2MEN1KMT2ATSHRNPC1 | |
| SCHEMBL29829681 | 0.83 | MEN1 (0.37) | NR4A2MEN1KMT2ATSHRNPC1 | |
| SCHEMBL20354688 | 0.83 | NR4A2 (0.42) | NR4A2MEN1KMT2ATSHRNPC1 | |
| SCHEMBL29559677 | 0.83 | NR4A2 (0.42) | NR4A2MEN1KMT2ATSHRNPC1 | |
| SCHEMBL23620131 | 0.80 | MEN1 (0.53) | MEN1KMT2ATSHRALDH1A1HPGD | |
| SCHEMBL30991273 | 0.80 | MEN1 (0.53) | MEN1KMT2ATSHRALDH1A1HPGD | |
| SCHEMBL21596684 | 0.80 | NR4A2 (0.42) | NR4A2MEN1KMT2ATSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469710-B | Pyridyl and pyrazinyl- (aza) indole sulfonamides | 优时比制药有限公司 | 2024-05-14 | — | — | CN | disclosed |