Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 5/20 | 0.35 |
| ▸ | LAP3 | P28838 | 4/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3099206 | 1.00 | ANPEP (0.35) | ANPEPLAP3ERAP1MMP1ALDH1A1 | |
| SCHEMBL523330 | 0.80 | LTA4H (0.35) | MMP1MMP8TDP1 | |
| SCHEMBL523329 | 0.80 | LTA4H (0.35) | MMP1MMP8TDP1 | |
| SCHEMBL3100524 | 0.79 | LAP3 (0.37) | ANPEPLAP3ERAP1MMP1ALDH1A1 | |
| SCHEMBL3100531 | 0.79 | LAP3 (0.37) | ANPEPLAP3ERAP1MMP1ALDH1A1 | |
| SCHEMBL3102891 | 0.78 | ANPEP (0.32) | ANPEPLAP3ERAP1MMP1ALDH1A1 | |
| SCHEMBL3102882 | 0.78 | ANPEP (0.32) | ANPEPLAP3ERAP1MMP1ALDH1A1 | |
| SCHEMBL14502966 | 0.77 | MEP1B (0.37) | MMP1MMP8MMP2MMP3CA1 | |
| SCHEMBL7763537 | 0.77 | MEP1B (0.37) | MMP1MMP8MMP2MMP3CA1 | |
| SCHEMBL3097218 | 0.76 | LAP3 (0.44) | ANPEPLAP3ERAP1MMP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |