Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.52 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167052 | 0.89 | ALDH1A1 (0.37) | TSHRGABRR1GABRR2BLMTDP1 | |
| SCHEMBL8461708 | 0.86 | PPARA (0.38) | TSHRGABRR1GABRR2BLMTDP1 | |
| SCHEMBL9726354 | 0.86 | TSHR (0.58) | TSHRGABRR1GABRR2BLMTDP1 | |
| SCHEMBL273087 | 0.86 | TSHR (0.58) | TSHRGABRR1GABRR2BLMTDP1 | |
| SCHEMBL8551677 | 0.83 | TSHR (0.55) | TSHRGABRR1GABRR2BLMTDP1 | |
| SCHEMBL8551672 | 0.83 | TSHR (0.55) | TSHRGABRR1GABRR2BLMTDP1 | |
| SCHEMBL1873474 | 0.79 | — | — | |
| SCHEMBL943834 | 0.79 | TAS1R3 (0.45) | TSHRGABRR1GABRR2BLMTDP1 | |
| SCHEMBL944831 | 0.79 | TAS1R3 (0.45) | TSHRGABRR1GABRR2BLMTDP1 | |
| SCHEMBL1873475 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118434791-A | Silicone monomer, contact lens composition and contact lens | 晶硕光学股份有限公司 | 2024-08-02 | — | — | CN | disclosed |