SCHEMBL30992115

SCHEMBL30992115

c1ccc(-c2cc(-c3ccccc3)cc(-c3ccccc3-c3ccccc3)c2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
BACE1 P56817 1/20 0.50
HSD17B10 Q99714 2/20 0.48
MAPK1 P28482 2/20 0.48
HPGD P15428 1/20 0.48
BCL2L1 Q07817 1/20 0.48
CYP2A6 P11509 1/20 0.48
ABL1 P00519 2/20 0.46
ABCB1 P08183 2/20 0.46
BCR P11274 2/20 0.46
NPC1 O15118 2/20 0.45
HTT P42858 2/20 0.45
RAB9A P51151 2/20 0.45
NPSR1 Q6W5P4 2/20 0.45
KDM4E B2RXH2 1/20 0.45
NTSR1 P30989 1/20 0.45
UHRF1 Q96T88 1/20 0.45
PTPN1 P18031 1/20 0.43
PTGS2 P35354 1/20 0.43
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29266808 0.97 ALDH1A1 (0.56) ALDH1A1BACE1HSD17B10MAPK1HPGD
Methylamine SCHEMBL28202149 0.89 ALDH1A1 (0.47) ALDH1A1BACE1HSD17B10MAPK1HPGD
SCHEMBL5549320 0.88 ALDH1A1 (0.53) ALDH1A1BACE1HSD17B10MAPK1HPGD
Biphenyl SCHEMBL1994657 0.87 ALDH1A1 (0.69) ALDH1A1BACE1HSD17B10MAPK1HPGD
SCHEMBL31720941 0.86 CYP1A2 (0.52) ALDH1A1BACE1CYP2A6ABL1ABCB1
SCHEMBL30216940 0.86 ALDH1A1 (0.50) ALDH1A1BACE1HSD17B10MAPK1HPGD
SCHEMBL20384016 0.86 ALDH1A1 (0.50) ALDH1A1BACE1HSD17B10MAPK1HPGD
SCHEMBL29618034 0.86 ALDH1A1 (0.50) ALDH1A1BACE1HSD17B10MAPK1HPGD
SCHEMBL30459454 0.86 ALDH1A1 (0.50) ALDH1A1BACE1HSD17B10MAPK1HPGD
SCHEMBL31720901 0.85 BACE1 (0.52) ALDH1A1BACE1HSD17B10MAPK1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118373803-A Synthesis method and application of fluorescent probe for lipase detection 广西大学 2024-07-23 CN disclosed