Methylamine

Methylamine

SCHEMBL28202149

CN.c1ccc(-c2cc(-c3ccccc3)cc(-c3ccccc3-c3cc(-c4ccccc4)cc(-c4ccccc4)c3)c2)cc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
HSD17B10 Q99714 3/20 0.44
MAOA P21397 1/20 0.42
CYP3A4 P08684 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
HTT P42858 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
BACE1 P56817 1/20 0.40
PTGS2 P35354 1/20 0.40
MEN1 O00255 1/20 0.40
APAF1 O14727 1/20 0.40
NPC1 O15118 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
THRB P10828 1/20 0.40
XBP1 P17861 1/20 0.40
PTBP1 P26599 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29266808 0.92 ALDH1A1 (0.56) ALDH1A1HSD17B10MAOACYP3A4TAAR1
SCHEMBL30992115 0.89 ALDH1A1 (0.53) ALDH1A1HSD17B10MAOAHTTSMN1; SMN2
Methylamine SCHEMBL27430084 0.83 ALDH1A1 (0.60) ALDH1A1HSD17B10CYP3A4TAAR1TDP1
SCHEMBL30913008 0.80 ALDH1A1 (0.73) ALDH1A1HSD17B10MAOACYP3A4TAAR1
SCHEMBL16503955 0.80 MAOA (0.50) ALDH1A1HSD17B10MAOACYP3A4TAAR1
SCHEMBL29210837 0.80 ALDH1A1 (0.73) ALDH1A1HSD17B10MAOACYP3A4TAAR1
SCHEMBL21230086 0.80 HTR7 (0.47) ALDH1A1SMN1; SMN2BACE1NPC1RAB9A
SCHEMBL26798848 0.80 PDCD1 (0.50) ALDH1A1MAOACYP3A4HTTSMN1; SMN2
SCHEMBL481505 0.80 ALDH1A1 (0.75) ALDH1A1HSD17B10MAOACYP3A4TAAR1
SCHEMBL8452262 0.80 ALDH1A1 (0.75) ALDH1A1HSD17B10MAOACYP3A4TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107759559-A Compound and organic electronic device thereof 彩丰精技股份有限公司 2018-03-06 CN disclosed