Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27329679 | 0.84 | KDM1A (0.40) | LMNAKMT2AMEN1HTTXDH | |
| SCHEMBL30992492 | 0.82 | XDH (0.40) | LMNAKMT2AKDM4EMEN1HTT | |
| SCHEMBL30992594 | 0.82 | XDH (0.36) | LMNAKMT2AKDM4EMEN1HTT | |
| SCHEMBL30992588 | 0.82 | PTGS2 (0.41) | LMNAKMT2AKDM4EMEN1HTT | |
| SCHEMBL30992431 | 0.81 | HAVCR2 (0.41) | LMNAKMT2AKDM4EMEN1HTT | |
| SCHEMBL30992444 | 0.76 | XDH (0.35) | KMT2AKDM4EMEN1HTTALDH1A1 | |
| SCHEMBL27329693 | 0.71 | ALDH1A1 (0.37) | LMNAKMT2AKDM4EMEN1HSD17B10 | |
| SCHEMBL27329413 | 0.68 | HAVCR2 (0.37) | KMT2AKDM4EMEN1ALDH1A1XDH | |
| SCHEMBL27329419 | 0.67 | HAVCR2 (0.38) | KDM4EALDH1A1XDHHPGDHAVCR2 | |
| SCHEMBL31404525 | 0.66 | KDM5A (0.42) | LMNAKMT2AKDM4EMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4633734-A1 | COMPOUNDS, COMPOSITIONS, AND MEZHODS OF TREATING DISORDERS ASSOCIATED WITH PROTEIN MISFOLDING | Wavebreak Therapeutics, LLC (US) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024129881-A1 | COMPOUNDS, COMPOSITIONS, AND MEZHODS OF TREATING DISORDERS ASSOCIATED WITH PROTEIN MISFOLDING | WAVEBREAK THERAPEUTICS LIMITED (US) | 2024-06-20 | — | — | WO | disclosed |