Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 4/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.34 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30993379 | 0.88 | CREBBP (0.41) | CREBBPKMT2ANR4A2BRD4TRIM24 | |
| SCHEMBL31022882 | 0.85 | GABRA1 (0.42) | GABRA1GABRB1NR4A2 | |
| SCHEMBL19657571 | 0.84 | CREBBP (0.41) | CREBBPKMT2ANR4A2BRD4TRIM24 | |
| SCHEMBL31023069 | 0.83 | GABRA1 (0.40) | CREBBPGABRA1GABRB1KMT2ANR4A2 | |
| SCHEMBL21024069 | 0.81 | CREBBP (0.41) | CREBBPBRD4TRIM24EP300BRD3 | |
| SCHEMBL31023051 | 0.80 | GABRA1 (0.37) | GABRA1GABRB1NR4A2 | |
| SCHEMBL30993555 | 0.78 | CREBBP (0.42) | CREBBPKMT2ANR4A2BRD4AR | |
| SCHEMBL30993042 | 0.77 | NR4A2 (0.39) | GABRA1GABRB1NR4A2 | |
| SCHEMBL30993739 | 0.76 | CREBBP (0.38) | CREBBPKMT2ANR4A2BRD4TRIM24 | |
| SCHEMBL4805445 | 0.76 | GABRA1 (0.41) | GABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-20 | — | — | WO | disclosed |