Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31023069 | 0.88 | GABRA1 (0.40) | GABRA1GABRB1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL30993004 | 0.85 | CREBBP (0.45) | GABRA1GABRB1NR4A2 | |
| SCHEMBL9288270 | 0.84 | AKR1C3 (0.39) | GABRA1GABRB1ACE2PRKAB2PRKAG1 | |
| SCHEMBL31023051 | 0.84 | GABRA1 (0.37) | GABRA1GABRB1NR4A2ALDH1A1 | |
| SCHEMBL19328315 | 0.83 | AKR1C4 (0.38) | GABRA1GABRB1ACE2PRKAB2PRKAG1 | |
| Lithium SCHEMBL17802201 | 0.83 | AKR1C3 (0.38) | GABRA1GABRB1ACE2PRKAB2PRKAG1 | |
| SCHEMBL30993042 | 0.82 | NR4A2 (0.39) | GABRA1GABRB1NR4A2 | |
| SCHEMBL4805445 | 0.80 | GABRA1 (0.41) | GABRA1GABRB1CYP1A2 | |
| SCHEMBL22462503 | 0.78 | AKR1C4 (0.48) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL30993539 | 0.75 | NR4A2 (0.36) | GABRA1GABRB1PRKAB2PRKAG1PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A9 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-08-02 | — | — | WO | disclosed |