Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31023108 | 0.85 | NR4A2 (0.55) | NR4A2HSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL30993555 | 0.85 | CREBBP (0.42) | NR4A2 | |
| SCHEMBL22462503 | 0.78 | AKR1C4 (0.48) | NR4A2CSNK2A2CSNK2BCSNK2A1PRKAG1 | |
| SCHEMBL30993503 | 0.76 | — | — | |
| SCHEMBL31022882 | 0.75 | GABRA1 (0.42) | NR4A2CSNK2A2CSNK2BCSNK2A1PRKAG1 | |
| SCHEMBL3196612 | 0.69 | KDM4E (0.48) | AKR1C3AKR1C2HSD17B10ALDH1A1KDM4E | |
| SCHEMBL20605026 | 0.69 | MYC (0.47) | CSNK2A2CSNK2BCSNK2A1PRKAG1PRKAA1 | |
| SCHEMBL9288270 | 0.69 | AKR1C3 (0.39) | NR4A2PRKAG1PRKAA1PRKAB1PRKAB2 | |
| SCHEMBL19328315 | 0.68 | AKR1C4 (0.38) | NR4A2PRKAG1PRKAA1PRKAB1PRKAB2 | |
| Lithium SCHEMBL17802201 | 0.68 | AKR1C3 (0.38) | NR4A2PRKAG1PRKAA1PRKAB1PRKAB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A9 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-08-02 | — | — | WO | disclosed |
| WO-2024130095-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-20 | — | — | WO | disclosed |