⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30993539 | 0.76 | NR4A2 (0.36) | — | |
| SCHEMBL20514353 | 0.73 | GPR84 (0.38) | — | |
| SCHEMBL19629565 | 0.73 | NMT1 (0.34) | — | |
| SCHEMBL30993555 | 0.71 | CREBBP (0.42) | — | |
| SCHEMBL31023108 | 0.71 | NR4A2 (0.55) | — | |
| SCHEMBL19629508 | 0.69 | EPRS1 (0.30) | — | |
| SCHEMBL19629549 | 0.69 | DYRK1A (0.45) | — | |
| SCHEMBL28992875 | 0.68 | AHR (0.41) | — | |
| SCHEMBL4685462 | 0.67 | IKBKB (0.47) | — | |
| SCHEMBL16608390 | 0.67 | MAPK1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-20 | — | — | WO | disclosed |