Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | HAT1 | O14929 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CD38 | P28907 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | BRD2 | P25440 | 1/20 | 0.31 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.31 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30993555 | 0.80 | CREBBP (0.42) | CREBBPNR4A2KMT2ACD38BRD4 | |
| SCHEMBL30993004 | 0.75 | CREBBP (0.45) | CREBBPNR4A2EP300KMT2ABRD4 | |
| SCHEMBL30993379 | 0.74 | CREBBP (0.41) | CREBBPNR4A2EP300KMT2ABRD4 | |
| SCHEMBL30993739 | 0.71 | CREBBP (0.38) | CREBBPNR4A2EP300KMT2ACD38 | |
| SCHEMBL30993716 | 0.69 | CREBBP (0.41) | CREBBPNR4A2HAT1EP300KMT2A | |
| SCHEMBL23227885 | 0.68 | NR4A2 (0.68) | CREBBPNR4A2MTNR1AMTNR1BGABRA1 | |
| SCHEMBL4120005 | 0.67 | SYK (0.46) | CREBBPNR4A2KMT2ABRD4 | |
| SCHEMBL30993339 | 0.67 | MEN1 (0.42) | CREBBPEP300KMT2ABRD4BRD3 | |
| SCHEMBL30993163 | 0.67 | CREBBP (0.39) | CREBBPNR4A2HAT1EP300KMT2A | |
| SCHEMBL16619233 | 0.65 | NR4A2 (0.52) | CREBBPNR4A2MTNR1AMTNR1BGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-20 | — | — | WO | disclosed |