Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.38 |
| ▸ | NHERF1 | O14745 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | HAT1 | O14929 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23622948 | 0.83 | F7 (0.51) | NR4A2NHERF1F7F3 | |
| SCHEMBL31022995 | 0.82 | NR4A2 (0.57) | CREBBPKMT2ANR4A2MTNR1AMTNR1B | |
| SCHEMBL30993751 | 0.79 | POLB (0.36) | PYGLNR4A2NHERF1NPC1F7 | |
| SCHEMBL30993612 | 0.79 | POLB (0.37) | KMT2APYGLNR4A2NHERF1NPC1 | |
| SCHEMBL30993024 | 0.78 | TYK2 (0.42) | PYGLNR4A2NHERF1NPC1F7 | |
| SCHEMBL30993163 | 0.77 | CREBBP (0.39) | CREBBPKMT2APYGLNR4A2NPC1 | |
| SCHEMBL30993573 | 0.73 | HTT (0.39) | KMT2ANPC1 | |
| SCHEMBL30993004 | 0.71 | CREBBP (0.45) | CREBBPKMT2ANR4A2EP300 | |
| SCHEMBL30993555 | 0.71 | CREBBP (0.42) | CREBBPKMT2ANR4A2 | |
| SCHEMBL25363319 | 0.70 | WDR5 (0.41) | CREBBPKMT2AWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-20 | — | — | WO | disclosed |