Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.34 |
| ▸ | CDC14B | O60729 | 2/20 | 0.33 |
| ▸ | CDC14A | Q9UNH5 | 2/20 | 0.33 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24472093 | 0.87 | ALOX5 (0.40) | ALOX5GGPS1CDC14BCDC14APTGES2 | |
| SCHEMBL17879922 | 0.86 | ALOX5 (0.42) | ALOX5GGPS1CDC14BCDC14APTGES2 | |
| SCHEMBL30214106 | 0.85 | ALOX5 (0.38) | ALOX5KDM4ECYP3A4HSD17B10BLM | |
| SCHEMBL29275761 | 0.85 | ALOX5 (0.38) | ALOX5KDM4ECYP3A4HSD17B10BLM | |
| SCHEMBL26687157 | 0.84 | ALOX5 (0.39) | ALOX5GGPS1CDC14BCDC14APTGES2 | |
| SCHEMBL26687144 | 0.84 | ALOX5 (0.39) | ALOX5GGPS1CDC14BCDC14APTGES2 | |
| SCHEMBL24472625 | 0.84 | ALOX5 (0.45) | ALOX5GGPS1CDC14BCDC14APTGES2 | |
| SCHEMBL24472105 | 0.84 | ALOX5 (0.45) | ALOX5GGPS1CDC14BCDC14APTGES2 | |
| SCHEMBL16883029 | 0.84 | ALOX5 (0.42) | ALOX5GGPS1CDC14BCDC14APTGES2 | |
| SCHEMBL24472078 | 0.84 | ALOX5 (0.45) | ALOX5GGPS1CDC14BCDC14APTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240262806-A1 | INHIBITORS OF NLRP3 | PCT THERAPEUTICS, INC. (US) | 2024-08-08 | — | — | US | claimed |
| CN-118302417-A | NLRP3 inhibitors | PTC医疗公司 | 2024-07-05 | — | — | CN | claimed |
| US-20240262806-A1 | INHIBITORS OF NLRP3 | PCT THERAPEUTICS, INC. (US) | 2024-08-08 | — | — | US | disclosed |
| CN-118302417-A | NLRP3 inhibitors | PTC医疗公司 | 2024-07-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240262806-A1 | INHIBITORS OF NLRP3 | NLRP3, NOD1, NLRP1 | ALOX5 1714/4885GGPS1 1673/4885CDC14B 4564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.