Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 6/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 6/20 | 0.37 |
| ▸ | RXRA | P19793 | 4/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29227936 | 1.00 | F11 (0.41) | F11GABRA1GABRG2GABRB3KLK1 | |
| SCHEMBL31174103 | 0.87 | F11 (0.40) | F11GABRA1GABRG2GABRB3NOTUM | |
| SCHEMBL31174090 | 0.84 | NOTUM (0.45) | F11GABRA1GABRG2GABRB3NOTUM | |
| SCHEMBL30994997 | 0.84 | F11 (0.39) | F11KLK1NOTUMARGABRA2 | |
| SCHEMBL29227930 | 0.84 | F11 (0.39) | F11KLK1NOTUMARGABRA2 | |
| SCHEMBL16971771 | 0.84 | F11 (0.38) | F11KLK1NOTUMRXRAGRIN1 | |
| SCHEMBL31174071 | 0.83 | F11 (0.40) | F11KLK1NOTUMRXRAGRIN1 | |
| SCHEMBL27003504 | 0.82 | F11 (0.40) | F11KLK1NOTUMRXRAGRIN1 | |
| SCHEMBL29839755 | 0.82 | F11 (0.40) | F11KLK1NOTUMRXRAGRIN1 | |
| SCHEMBL24633397 | 0.81 | F11 (0.43) | F11GABRA1GABRG2GABRB3KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4737457-A1 | POLYSUBSTITUTED MACROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shenzhen Salubris Pharmaceuticals Co., Ltd. (CN) | 2026-05-06 | — | — | EP | disclosed |
| CN-118126046-A | Substituted macrocyclic compound, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2024-06-04 | — | — | CN | disclosed |