Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 5/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 5/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ACVR2A | P27037 | 2/20 | 0.34 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31174090 | 0.88 | NOTUM (0.45) | F11KLKB1F2RXRAGRIN1 | |
| SCHEMBL29227936 | 0.87 | F11 (0.41) | F11KLKB1RXRAGRIN1GRIN2B | |
| SCHEMBL30995051 | 0.87 | F11 (0.41) | F11KLKB1RXRAGRIN1GRIN2B | |
| SCHEMBL31174106 | 0.85 | NOTUM (0.47) | F11NOTUMGRM2 | |
| SCHEMBL16971357 | 0.83 | F11 (0.37) | F11KLKB1F2RXRAGRIN1 | |
| SCHEMBL24633365 | 0.78 | F11 (0.43) | F11KLKB1ACVR2ATGFBR2 | |
| SCHEMBL30995011 | 0.78 | F11 (0.43) | F11KLKB1ACVR2ATGFBR2 | |
| SCHEMBL16974697 | 0.75 | NOTUM (0.43) | F11RXRAGRIN1GRIN2BNOTUM | |
| SCHEMBL30995035 | 0.74 | ADORA2B (0.45) | ADORA2BACVR2ATGFBR2DYRK1AGRM5 | |
| SCHEMBL16971893 | 0.74 | NOTUM (0.40) | F11KLKB1F2RXRAGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118852163-A | Macrocyclic compound containing heteroatoms, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2024-10-29 | — | — | CN | disclosed |