Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8018111 | 0.81 | PAX8 (0.55) | PAX8BRD4CREBBPRAB9AMEN1 | |
| SCHEMBL16197281 | 0.80 | PAX8 (0.50) | PAX8BRD4CREBBPRAB9AMEN1 | |
| SCHEMBL7531272 | 0.80 | PAX8 (0.50) | PAX8BRD4CREBBPRAB9AMEN1 | |
| SCHEMBL25960281 | 0.79 | PAX8 (0.49) | PAX8BRD4CREBBPRAB9AMEN1 | |
| SCHEMBL13674397 | 0.79 | PAX8 (0.49) | PAX8BRD4CREBBPRAB9AMEN1 | |
| SCHEMBL16856539 | 0.79 | PAX8 (0.49) | PAX8BRD4CREBBPRAB9AMEN1 | |
| SCHEMBL14090333 | 0.79 | PAX8 (0.49) | PAX8BRD4CREBBPRAB9AMEN1 | |
| SCHEMBL27621553 | 0.78 | ALDH1A1 (0.47) | PAX8BRD4CREBBPNR1H3RXRA | |
| SCHEMBL4615305 | 0.78 | NR1H4 (0.56) | PAX8BRD4CREBBPRAB9AMEN1 | |
| SCHEMBL23092452 | 0.77 | SLC6A4 (0.48) | PAX8BRD4IDO1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024156288-A1 | DNMT1 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | SHANGHAI KYGENT PHARMACEUTICAL CO., LTD (CN) | 2024-08-02 | — | — | WO | disclosed |