Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 8/20 | 0.53 |
| ▸ | MMP2 | P08253 | 6/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30995155 | 1.00 | KDM4E (0.60) | KDM4EALDH1A1HPGDRAB9ALMNA | |
| SCHEMBL8959587 | 0.88 | KDM4E (0.67) | KDM4EALDH1A1HPGDRAB9ALMNA | |
| SCHEMBL4041495 | 0.86 | KDM4E (0.63) | KDM4EALDH1A1HPGDRAB9ALMNA | |
| SCHEMBL22620718 | 0.84 | KDM4E (0.62) | KDM4EALDH1A1HPGDRAB9ALMNA | |
| SCHEMBL1397950 | 0.84 | KDM4E (0.62) | KDM4EALDH1A1HPGDRAB9ALMNA | |
| SCHEMBL3276358 | 0.83 | ALOX15 (0.63) | KDM4EALDH1A1HPGDRAB9ALMNA | |
| SCHEMBL29641398 | 0.83 | ALOX15 (0.63) | KDM4EALDH1A1HPGDRAB9ALMNA | |
| SCHEMBL23049705 | 0.83 | ALOX15 (0.63) | KDM4EALDH1A1HPGDRAB9ALMNA | |
| SCHEMBL31423148 | 0.83 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDRAB9ALMNA | |
| SCHEMBL17494267 | 0.83 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530160-A | Aromatic heterocyclic compound, preparation method and application thereof | 上海翊石医药科技有限公司 | 2024-08-23 | — | — | CN | disclosed |