Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.47 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | LIPC | P11150 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30995135 | 0.82 | ALDH1A1 (0.46) | CCR2PLA2G10CYP11B2ALDH1A1SMN1; SMN2 | |
| SCHEMBL30995214 | 0.82 | USP2 (0.43) | ALDH1A1SMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL30995232 | 0.80 | ALDH1A1 (0.55) | CCR2PLA2G10ALDH1A1TSHRMEN1 | |
| SCHEMBL31339892 | 0.80 | OGFRL1 (0.42) | ALDH1A1MEN1KMT2ALIPCLIPG | |
| SCHEMBL30995185 | 0.80 | MCL1 (0.46) | CCR2ALDH1A1TSHRKMT2AHTR7 | |
| SCHEMBL30995124 | 0.78 | ALDH1A1 (0.42) | CYP11B2ALDH1A1SMN1; SMN2USP2PKM | |
| SCHEMBL30995156 | 0.77 | PLA2G10 (0.43) | CCR2PLA2G10PLA2G2AALDH1A1SMN1; SMN2 | |
| SCHEMBL30995241 | 0.76 | CYP11B2 (0.48) | CCR2PLA2G10PLA2G2ACYP11B2ALDH1A1 | |
| SCHEMBL9816566 | 0.76 | ALDH1A1 (0.54) | CCR2ALDH1A1TSHRDAOKDM4E | |
| SCHEMBL2140750 | 0.75 | MCL1 (0.57) | CCR2PLA2G10PLA2G2APLA2G5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530160-A | Aromatic heterocyclic compound, preparation method and application thereof | 上海翊石医药科技有限公司 | 2024-08-23 | — | — | CN | disclosed |