Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30995252 | 0.95 | PLA2G10 (0.42) | PLA2G10PLA2G2APIK3CAPRKDCABL1 | |
| SCHEMBL30995164 | 0.84 | PIK3CA (0.41) | PLA2G10PLA2G2APIK3CAPRKDCALDH1A1 | |
| SCHEMBL30995119 | 0.81 | PIK3CA (0.38) | PLA2G10PLA2G2APIK3CAPRKDCABL1 | |
| SCHEMBL30995135 | 0.80 | ALDH1A1 (0.46) | PLA2G10ALDH1A1TSHRDAOMCL1 | |
| SCHEMBL30995228 | 0.79 | NOD2 (0.41) | PLA2G10PLA2G2APIK3CAPRKDCALDH1A1 | |
| SCHEMBL30995232 | 0.78 | ALDH1A1 (0.55) | PLA2G10ALDH1A1TSHRDAOMCL1 | |
| SCHEMBL30995185 | 0.78 | MCL1 (0.46) | ALDH1A1TSHRDAOMCL1L3MBTL1 | |
| SCHEMBL30995189 | 0.77 | CCR2 (0.47) | PLA2G10PLA2G2AALDH1A1TSHRDAO | |
| SCHEMBL30995229 | 0.75 | ABL1 (0.37) | PLA2G10PLA2G2APIK3CAPRKDCABL1 | |
| SCHEMBL30995241 | 0.74 | CYP11B2 (0.48) | PLA2G10PLA2G2AALDH1A1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530160-A | Aromatic heterocyclic compound, preparation method and application thereof | 上海翊石医药科技有限公司 | 2024-08-23 | — | — | CN | disclosed |