Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30995440 | 0.91 | THRB (0.36) | THRBKMT2ATDP1KDM4ENSD2 | |
| SCHEMBL30995434 | 0.89 | THRB (0.33) | THRBKMT2ATDP1HRH3BACE1 | |
| SCHEMBL30995439 | 0.84 | KMT2A (0.46) | THRBKMT2APDE4DMAPTTLR7 | |
| SCHEMBL30995487 | 0.82 | TLR8 (0.42) | THRBKMT2APDE4D | |
| SCHEMBL30995445 | 0.81 | ENPP2 (0.42) | THRBKMT2AKDM4EPSEN1PSEN2 | |
| SCHEMBL30995464 | 0.80 | THRB (0.41) | THRBKMT2AKDM4ENSD2ALDH1A1 | |
| SCHEMBL30995468 | 0.78 | THRB (0.36) | THRBKMT2APDE4DBACE1RXFP1 | |
| SCHEMBL30995500 | 0.78 | MAP4K4 (0.43) | THRBKMT2AKDM4ENSD2ALDH1A1 | |
| SCHEMBL30995456 | 0.77 | NOTUM (0.41) | THRBKMT2ATDP1KDM4ENSD2 | |
| SCHEMBL203392 | 0.72 | THRB (0.39) | THRBKMT2APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530224-A | Pyrimidinone compound and application thereof | 深圳安泰维生物医药有限公司 | 2024-08-23 | — | — | CN | disclosed |