Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30995445 | 0.98 | ENPP2 (0.42) | TLR8MEN1KMT2AENPP2THRB | |
| SCHEMBL30995439 | 0.95 | KMT2A (0.46) | TLR8MEN1KMT2ATHRBADORA3 | |
| SCHEMBL30995464 | 0.89 | THRB (0.41) | MEN1KMT2ATHRBADORA3CRHR1 | |
| SCHEMBL30995468 | 0.84 | THRB (0.36) | MEN1KMT2ATHRBPDE4D | |
| SCHEMBL30995481 | 0.82 | THRB (0.35) | KMT2ATHRBPDE4D | |
| SCHEMBL30995456 | 0.82 | NOTUM (0.41) | MEN1KMT2ATHRBADORA3 | |
| SCHEMBL30995500 | 0.80 | MAP4K4 (0.43) | KMT2ATHRBCRHR1 | |
| SCHEMBL30995440 | 0.79 | THRB (0.36) | KMT2ATHRBADORA3KDR | |
| SCHEMBL254046 | 0.78 | TLR8 (0.50) | TLR8MEN1KMT2AKDR | |
| SCHEMBL26024454 | 0.77 | TLR8 (0.41) | TLR8PDE4DKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530224-A | Pyrimidinone compound and application thereof | 深圳安泰维生物医药有限公司 | 2024-08-23 | — | — | CN | disclosed |