Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TERT | O14746 | 1/20 | 0.53 |
| ▸ | METAP2 | P50579 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27207566 | 0.89 | ALDH1A1 (0.62) | SMN1; SMN2POLBPTK2HDAC1HDAC2 | |
| SCHEMBL31411197 | 0.85 | SMN1; SMN2 (0.63) | SMN1; SMN2HPGDNPSR1TSHRALDH1A1 | |
| SCHEMBL31294061 | 0.78 | MEN1 (0.59) | SMN1; SMN2HPGDALDH1A1LMNAGAA | |
| SCHEMBL27175659 | 0.77 | ALDH1A1 (0.62) | HPGDNPSR1TSHRPOLBALDH1A1 | |
| SCHEMBL5819247 | 0.77 | SMN1; SMN2 (0.68) | SMN1; SMN2HPGDNPSR1TSHRPOLB | |
| SCHEMBL5819243 | 0.77 | SMN1; SMN2 (0.68) | SMN1; SMN2HPGDNPSR1TSHRPOLB | |
| SCHEMBL30828808 | 0.77 | MEN1 (0.63) | SMN1; SMN2HPGDPTK2HDAC1HDAC2 | |
| SCHEMBL27171349 | 0.77 | MEN1 (0.63) | SMN1; SMN2HPGDPTK2HDAC1HDAC2 | |
| SCHEMBL30841601 | 0.76 | ALDH1A1 (0.54) | SMN1; SMN2HPGDNPSR1TSHRPOLB | |
| SCHEMBL27097362 | 0.76 | ALDH1A1 (0.54) | SMN1; SMN2HPGDNPSR1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12065411-B1 | Methyl 4-((5-(3-fluorophenyl)-4-phenyl-4H-1,2,4-triazol-3-ylthio)methyl)benzoate as an antimicrobial compound | King Faisal University (SA) | 2024-08-20 | — | — | US | claimed |
| US-12065411-B1 | Methyl 4-((5-(3-fluorophenyl)-4-phenyl-4H-1,2,4-triazol-3-ylthio)methyl)benzoate as an antimicrobial compound | King Faisal University (SA) | 2024-08-20 | — | — | US | disclosed |
| US-12065411-B1 | Methyl 4-((5-(3-fluorophenyl)-4-phenyl-4H-1,2,4-triazol-3-ylthio)methyl)benzoate as an antimicrobial compound | King Faisal University (SA) | 2024-08-20 | — | — | US | disclosed |
| US-12065411-B1 | Methyl 4-((5-(3-fluorophenyl)-4-phenyl-4H-1,2,4-triazol-3-ylthio)methyl)benzoate as an antimicrobial compound | King Faisal University (SA) | 2024-08-20 | — | — | US | disclosed |
| US-12054464-B1 | Methyl 4-((5-(3-fluorophenyl)-4-phenyl-4H-1,2,4-triazol-3-ylthio)methyl)benzoate as an antimicrobial compound | King Faisal University (SA) | 2024-08-06 | — | — | US | disclosed |
| US-12054464-B1 | Methyl 4-((5-(3-fluorophenyl)-4-phenyl-4H-1,2,4-triazol-3-ylthio)methyl)benzoate as an antimicrobial compound | King Faisal University (SA) | 2024-08-06 | — | — | US | disclosed |
| US-12054464-B1 | Methyl 4-((5-(3-fluorophenyl)-4-phenyl-4H-1,2,4-triazol-3-ylthio)methyl)benzoate as an antimicrobial compound | King Faisal University (SA) | 2024-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12065411-B1 | Methyl 4-((5-(3-fluorophenyl)-4-phenyl-4H-1,2,4-triazol-3-ylthio)methyl)benzoate as an antimicrobial compound | TLR4, CASP4, TET3 | SMN1; SMN2 4098/4885HPGD 3645/4885NPSR1 4763/4885 |
| US-12054464-B1 | Methyl 4-((5-(3-fluorophenyl)-4-phenyl-4H-1,2,4-triazol-3-ylthio)methyl)benzoate as an antimicrobial compound | TLR4, CASP4, TET3 | SMN1; SMN2 4098/4885HPGD 3645/4885NPSR1 4763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.