Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819247 | 0.89 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1LMNAGAAHPGD | |
| SCHEMBL28485044 | 0.77 | LMNA (0.54) | SMN1; SMN2ALDH1A1LMNAGAAHPGD | |
| SCHEMBL30997232 | 0.77 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1LMNAGAAHPGD | |
| SCHEMBL28478277 | 0.76 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1LMNAGAAHPGD | |
| SCHEMBL24019811 | 0.72 | HPGD (0.76) | ALDH1A1LMNAGAAHPGDNPSR1 | |
| SCHEMBL3916950 | 0.71 | RAB9A (0.61) | SMN1; SMN2ALDH1A1LMNAGAAHPGD | |
| SCHEMBL4210833 | 0.69 | OPRK1 (0.74) | SMN1; SMN2ALDH1A1NPSR1TSHRTHRB | |
| SCHEMBL4215568 | 0.69 | HDAC2 (0.58) | SMN1; SMN2ALDH1A1LMNAGAAHPGD | |
| SCHEMBL1073002 | 0.69 | NPC1 (1.00) | SMN1; SMN2ALDH1A1LMNAGAAHPGD | |
| SCHEMBL24019576 | 0.69 | HPGD (0.74) | ALDH1A1LMNAGAAHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093518-A2 | THIENYL COMPOUNDS FOR TREATING VIRUS-RELATED CONDITIONS | APATH, LLC (US) | 2006-09-08 | — | — | WO | disclosed |