Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.42 |
| ▸ | LOX | P28300 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.40 |
| ▸ | FEN1 | P39748 | 2/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 8/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19124891 | 1.00 | LOXL2 (0.42) | LOXL2LOXALOX5APFEN1RIPK2 | |
| SCHEMBL15901459 | 0.86 | LOXL2 (0.42) | LOXL2LOXALOX5APFEN1RIPK2 | |
| SCHEMBL29769062 | 0.86 | LOXL2 (0.42) | LOXL2LOXALOX5APFEN1RIPK2 | |
| SCHEMBL24998894 | 0.84 | LOXL2 (0.40) | LOXL2LOXALOX5APFEN1RIPK2 | |
| SCHEMBL23193922 | 0.84 | PLA2G7 (0.40) | LOXL2LOXALOX5APFEN1RIPK2 | |
| SCHEMBL29769056 | 0.84 | LOXL2 (0.40) | LOXL2LOXALOX5APFEN1RIPK2 | |
| SCHEMBL24385766 | 0.83 | LOXL2 (0.39) | LOXL2LOXALOX5APFEN1RIPK2 | |
| SCHEMBL21098806 | 0.81 | ALOX5AP (0.42) | LOXL2LOXALOX5APFEN1RIPK2 | |
| SCHEMBL30753333 | 0.81 | LOXL2 (0.38) | LOXL2LOXALOX5APFEN1RIPK2 | |
| SCHEMBL31261887 | 0.78 | ALOX5AP (0.40) | LOXL2LOXALOX5APFEN1RIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119320393-A | Bicyclo [5,6] imidazole pyrimidinone derivative, preparation method and application thereof | 上海枢境生物科技有限公司 | 2025-01-17 | — | — | CN | disclosed |
| CN-118221687-B | Bicyclo [5,6] imidazole pyrimidinone derivative, preparation method and application thereof | 上海枢境生物科技有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-118221687-A | Bicyclo [5,6] imidazole pyrimidinone derivative, preparation method and application thereof | 上海枢境生物科技有限公司 | 2024-06-21 | — | — | CN | disclosed |