Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 4/20 | 0.49 |
| ▸ | NCF1 | P14598 | 2/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ILK | Q13418 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29862942 | 0.98 | KMT2A (0.49) | HRH4MEN1KMT2APOLBACHE | |
| SCHEMBL29636853 | 0.87 | NCF1 (0.42) | HRH4MEN1KMT2APOLBACHE | |
| SCHEMBL31677954 | 0.82 | POLB (0.49) | POLBACHENCF1HTR3AALDH1A1 | |
| Hydrochloric Acid SCHEMBL29862880 | 0.81 | KMT2A (0.46) | HRH4MEN1KMT2APOLBACHE | |
| SCHEMBL29636762 | 0.79 | NCF1 (0.38) | MEN1KMT2APOLBACHENCF1 | |
| Hydrochloric Acid SCHEMBL28834209 | 0.77 | HRH4 (0.46) | HRH4MEN1KMT2AILKNPC1 | |
| SCHEMBL8567840 | 0.76 | POLB (0.47) | HRH4MEN1KMT2APOLBSLC18A3 | |
| SCHEMBL29636644 | 0.76 | KMT2A (0.42) | HRH4MEN1KMT2APOLBACHE | |
| SCHEMBL28967174 | 0.76 | KMT2A (0.42) | HRH4MEN1KMT2APOLBACHE | |
| SCHEMBL23015130 | 0.74 | ACP1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024119028-A1 | SUBSTITUTED QUINOLINE DERIVATIVES HAVING SOS1 INHIBITION ACTIVITIES AND USES THEREOF | ACCUTAR BIOTECHNOLOGY, INC. (US) | 2024-06-06 | — | — | WO | disclosed |