Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 2/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29937376 | 0.88 | ALDH1A1 (0.56) | ALDH1A1CYP2D6ATMNPSR1POLB | |
| SCHEMBL28515732 | 0.82 | ALDH1A1 (0.50) | ALDH1A1CYP2D6ATMNPSR1POLB | |
| SCHEMBL29937273 | 0.78 | ALDH1A1 (0.55) | ALDH1A1CYP2D6ATMNPSR1POLB | |
| SCHEMBL28996034 | 0.77 | ALDH1A1 (0.56) | ALDH1A1CYP2D6ATMNPSR1POLB | |
| SCHEMBL29687392 | 0.77 | ALDH1A1 (0.56) | ALDH1A1CYP2D6ATMNPSR1POLB | |
| SCHEMBL29975689 | 0.76 | ALDH1A1 (0.52) | ALDH1A1CYP2D6ATMNPSR1POLB | |
| SCHEMBL29433996 | 0.73 | ALDH1A1 (0.58) | ALDH1A1CYP2D6ATMNPSR1POLB | |
| SCHEMBL28729752 | 0.73 | ALDH1A1 (0.58) | ALDH1A1CYP2D6ATMNPSR1POLB | |
| SCHEMBL29936900 | 0.71 | ALDH1A1 (0.56) | ALDH1A1CYP2D6ATMNPSR1POLB | |
| Hydrochloric Acid SCHEMBL7522555 | 0.70 | ALDH1A1 (0.68) | ALDH1A1CYP2D6ATMNPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239788-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239788-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | KRAS, NRAS, HRAS | ALDH1A1 2871/4885CYP2D6 2875/4885ATM 701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.