SCHEMBL30998804

SCHEMBL30998804

c1ccc(CN(Cc2ccccc2)Nc2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
NPSR1 Q6W5P4 1/20 0.47
TSHR P16473 2/20 0.46
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43
AOC3 Q16853 1/20 0.43
NR3C1 P04150 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
IDO1 P14902 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
NR3C2 P08235 1/20 0.40
LMNA P02545 1/20 0.40
CA2 P00918 1/20 0.39
CARM1 Q86X55 1/20 0.38
PRMT6 Q96LA8 1/20 0.38
PRMT8 Q9NR22 1/20 0.38
EPHX2 P34913 1/20 0.38
CTSD P07339 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7482720 0.81 KCNH2 (0.50) ALDH1A1TSHR
SCHEMBL7167305 0.81 LTA4H (0.52) ALDH1A1NPSR1TSHRRAB9AL3MBTL1
SCHEMBL6237448 0.77 ALDH1A1 (0.54) ALDH1A1NPSR1TSHRCRHBPCRHR2
SCHEMBL28652733 0.77 ALDH1A1 (0.52) ALDH1A1NPSR1TSHRAOC3NPC1
SCHEMBL50189 0.73 L3MBTL1 (0.52) ALDH1A1NPSR1TSHRNPC1RAB9A
SCHEMBL10523248 0.73 AOC3 (0.50) ALDH1A1NPSR1TSHRAOC3NPC1
Hydrochloric Acid SCHEMBL11760188 0.71 L3MBTL1 (0.50) ALDH1A1NPSR1TSHRNPC1RAB9A
SCHEMBL1793161 0.71 ALDH1A1 (0.46) ALDH1A1TSHRAOC3NPC1RAB9A
SCHEMBL1348045 0.71 ALDH1A1 (0.46) ALDH1A1TSHRAOC3NPC1RAB9A
Hydrochloric Acid SCHEMBL9638886 0.71 L3MBTL1 (0.50) ALDH1A1NPSR1TSHRNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118373817-A Method for preparing meihai Qu Linnai disulfonate by one-pot method 湖南九维生物医药有限公司 2024-07-23 CN claimed
CN-118373817-A Method for preparing meihai Qu Linnai disulfonate by one-pot method 湖南九维生物医药有限公司 2024-07-23 CN disclosed