Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.78 |
| ▸ | TYR | P14679 | 1/20 | 0.58 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Licoagrocarpin SCHEMBL30999863 | 1.00 | PTPN1 (0.78) | PTPN1TYRHSD17B1MAPTMAPK1 | |
| SCHEMBL29571779 | 0.90 | PTPN1 (0.63) | PTPN1TYRHSD17B1MAPTMAPK1 | |
| SCHEMBL29572116 | 0.86 | PTPN1 (0.88) | PTPN1TYRHSD17B1HSP90AA1 | |
| Erybreadin C SCHEMBL31237899 | 0.85 | PTPN1 (1.00) | PTPN1HSD17B1MAOAMAOBHSP90AA1 | |
| Erybraedin A SCHEMBL29572007 | 0.83 | PTPN1 (0.76) | PTPN1TYRHSD17B1HSP90AA1CYP19A1 | |
| Vesticarpan SCHEMBL13731396 | 0.82 | MAOA (0.58) | PTPN1TYRMAPTMAPK1TDP1 | |
| SCHEMBL4727259 | 0.81 | PTGS1 (0.63) | PTPN1TYRMAPTMAPK1TDP1 | |
| SCHEMBL31357398 | 0.81 | PTGS1 (0.63) | PTPN1TYRMAPTMAPK1TDP1 | |
| SCHEMBL27836059 | 0.76 | MAOA (0.73) | PTPN1MAPTMAPK1TDP1MAOA | |
| SCHEMBL29906138 | 0.75 | PTPN1 (0.69) | PTPN1HSD17B1MAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118345132-A | Biosynthesis method of glabridin precursor 4' -O-Methylpreglabridin | 南京中医药大学 | 2024-07-16 | — | — | CN | claimed |
| CN-118345132-A | Biosynthesis method of glabridin precursor 4' -O-Methylpreglabridin | 南京中医药大学 | 2024-07-16 | — | — | CN | disclosed |