Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31357398 | 1.00 | PTGS1 (0.63) | PTGS1MAPK1MAPTTDP1MAOA | |
| Vesticarpan SCHEMBL13731396 | 0.89 | MAOA (0.58) | PTGS1MAPK1MAPTTDP1MAOA | |
| SCHEMBL27836059 | 0.83 | MAOA (0.73) | PTGS1MAPK1MAPTTDP1MAOA | |
| Licoagrocarpin SCHEMBL30999863 | 0.81 | PTPN1 (0.78) | MAPK1MAPTTDP1MAOAMAOB | |
| Licoagrocarpin SCHEMBL30999862 | 0.81 | PTPN1 (0.78) | MAPK1MAPTTDP1MAOAMAOB | |
| Homopterocarpin SCHEMBL12810250 | 0.81 | MAPT (0.80) | MAPK1MAPTTDP1MAOAMAOB | |
| Homopterocarpin SCHEMBL12998414 | 0.81 | MAPT (0.80) | MAPK1MAPTTDP1MAOAMAOB | |
| Homopterocarpin SCHEMBL29366996 | 0.81 | MAPT (0.80) | MAPK1MAPTTDP1MAOAMAOB | |
| Homopterocarpin SCHEMBL31237481 | 0.81 | MAPT (0.80) | MAPK1MAPTTDP1MAOAMAOB | |
| Homopterocarpin SCHEMBL12810803 | 0.81 | MAPT (0.80) | MAPK1MAPTTDP1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809627-B2 | Plant isoflavone and isoflavanone O-methyltransferase genes | THE SAMUEL ROBERTS NOBLE FOUNDATION, INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-20080317880-A1 | PLANT ISOFLAVONE AND ISOFLAVANONE O-METHYLTRANSFERASE GENES | THE SAMUEL ROBERTS NOBLE FOUNDATION | 2008-12-25 | — | — | US | disclosed |
| WO-2008022265-A2 | PLANT ISOFLAVONE AND ISOFLAVANONE O-METHYLTRANSFERASE GENES | THE SAMUEL ROBERTS NOBLE FOUNDATION, INC. (US) | 2008-02-21 | — | — | WO | disclosed |