Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6719388 | 0.84 | MAPT (0.45) | PARP1NPC1 | |
| SCHEMBL30999982 | 0.75 | ALDH1A1 (0.30) | — | |
| SCHEMBL25344514 | 0.71 | ALDH1A1 (0.39) | NPC1 | |
| SCHEMBL6730106 | 0.71 | ALDH1A1 (0.39) | NPC1 | |
| SCHEMBL6723898 | 0.68 | PNP (0.36) | NPC1HSD17B10 | |
| SCHEMBL6719104 | 0.68 | NPC1 (0.53) | PARP1NPC1 | |
| SCHEMBL6726785 | 0.68 | NPC1 (0.37) | NPC1 | |
| SCHEMBL6722438 | 0.67 | ATM (0.38) | NPC1 | |
| SCHEMBL6722467 | 0.67 | PDE4A (0.60) | HSD17B10 | |
| SCHEMBL6719573 | 0.67 | GRIK1 (0.47) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658262-A1 | BICYCLIC IMIDE COMPOUNDS AS TRPA1 INHIBITORS | D.E. Shaw Research, LLC (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163333-A1 | BICYCLIC IMIDE COMPOUNDS AS TRPA1 INHIBITORS | D. E. SHAW RESEARCH, LLC (US) | 2024-08-08 | — | — | WO | disclosed |