Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | DUT | P33316 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6719104 | 0.77 | NPC1 (0.53) | NPC1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL6726529 | 0.77 | ALDH1A1 (0.33) | NPC1ALDH1A1PKMKDM4EPDE5A | |
| SCHEMBL6726785 | 0.76 | NPC1 (0.37) | NPC1ALDH1A1MAPTEGFRIGF1R | |
| SCHEMBL30791436 | 0.74 | CYP1A2 (0.55) | NPC1ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL5129680 | 0.72 | NPC1 (0.37) | NPC1MAPTERCC5 | |
| SCHEMBL6722410 | 0.72 | EGFR (0.39) | NPC1ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL6723712 | 0.72 | ADORA2B (0.37) | NPC1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL1244925 | 0.71 | MAPT (0.37) | NPC1MAPTKDM4ETP53SMN1; SMN2 | |
| SCHEMBL18689573 | 0.70 | GRIK1 (0.48) | GRIK1GRIA1ALDH1A1KMT2APKM | |
| SCHEMBL25344514 | 0.69 | ALDH1A1 (0.39) | NPC1ALDH1A1PKMMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673804-B1 | PREVENTING OR TREATING ARTHRITIS (PARTICULARLY OSTEOARTHRITIS) OR INHIBITING METASTASIS, INVASION OR GROWTH OF CANCER (PARTICULARLY BREAST CANCER) | SANKYO COMPANY, LIMITED (JP) | 2004-01-06 | — | — | US | disclosed |
| EP-1069110-A1 | SULFONAMIDE DERIVATIVES | Sankyo Company Limited (JP) | 2001-01-17 | — | — | EP | disclosed |