Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25344514 | 0.83 | ALDH1A1 (0.39) | ALDH1A1NPC1 | |
| SCHEMBL10479252 | 0.72 | LMNA (0.44) | — | |
| SCHEMBL6722438 | 0.72 | ATM (0.38) | ALDH1A1NPC1 | |
| SCHEMBL25344141 | 0.71 | NPC1 (0.35) | NPC1 | |
| SCHEMBL6719388 | 0.71 | MAPT (0.45) | NPC1 | |
| SCHEMBL30999963 | 0.71 | PARP1 (0.32) | NPC1 | |
| SCHEMBL6719104 | 0.71 | NPC1 (0.53) | ALDH1A1NPC1 | |
| SCHEMBL6723898 | 0.71 | PNP (0.36) | ALDH1A1NPC1 | |
| SCHEMBL6719796 | 0.71 | DUT (0.37) | ALDH1A1NPC1 | |
| SCHEMBL6723712 | 0.71 | ADORA2B (0.37) | ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673804-B1 | PREVENTING OR TREATING ARTHRITIS (PARTICULARLY OSTEOARTHRITIS) OR INHIBITING METASTASIS, INVASION OR GROWTH OF CANCER (PARTICULARLY BREAST CANCER) | SANKYO COMPANY, LIMITED (JP) | 2004-01-06 | — | — | US | disclosed |
| EP-1069110-A1 | SULFONAMIDE DERIVATIVES | Sankyo Company Limited (JP) | 2001-01-17 | — | — | EP | disclosed |