Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31000020 | 0.83 | CDK2 (0.45) | DYRK1ASMN1; SMN2GAAPOLBKMT2A | |
| SCHEMBL8363843 | 0.83 | MAPT (0.42) | DYRK1ASMN1; SMN2POLBSTAT1KMT2A | |
| SCHEMBL30999992 | 0.79 | CDK2 (0.66) | SMN1; SMN2GAAKMT2AMAPTMEN1 | |
| SCHEMBL17234004 | 0.79 | RAB9A (0.41) | SMN1; SMN2ABCG2KMT2AMAPTRAB9A | |
| SCHEMBL4882428 | 0.78 | MGLL (0.47) | SMN1; SMN2POLBALDH1A1HTT | |
| SCHEMBL17224016 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP1A2KMT2AMAPTRAB9A | |
| SCHEMBL6778003 | 0.78 | DYRK1A (0.45) | DYRK1ASMN1; SMN2GAACYP1A2CSNK2A2 | |
| SCHEMBL17234181 | 0.78 | MAPT (0.58) | SMN1; SMN2POLBKMT2AMAPTRAB9A | |
| SCHEMBL17233947 | 0.77 | SMN1; SMN2 (0.42) | SMN1; SMN2CYP1A2POLBKMT2AMAPT | |
| SCHEMBL17233990 | 0.77 | MAPT (0.38) | DYRK1ASMN1; SMN2POLBSTAT1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658264-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USE TO INHIBIT PROTEIN AGGREGATION | Purdue Research Foundation (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163907-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USE TO INHIBIT PROTEIN AGGREGATION | PURDUE RESEARCH FOUNDATION (US) | 2024-08-08 | — | — | WO | disclosed |