Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31000020 | 0.83 | CDK2 (0.45) | CDK2ALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL6600101 | 0.80 | CDK2 (1.00) | CDK2ALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL30999993 | 0.79 | DYRK1A (0.51) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL4884039 | 0.75 | TP53 (0.45) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL8363843 | 0.74 | MAPT (0.42) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL17234181 | 0.73 | MAPT (0.58) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL17224014 | 0.73 | CYP1A2 (0.48) | CDK2ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6754266 | 0.72 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL27841700 | 0.72 | MEN1 (0.74) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL27406580 | 0.72 | LMNA (0.70) | CDK2ALDH1A1SMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658264-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USE TO INHIBIT PROTEIN AGGREGATION | Purdue Research Foundation (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163907-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USE TO INHIBIT PROTEIN AGGREGATION | PURDUE RESEARCH FOUNDATION (US) | 2024-08-08 | — | — | WO | disclosed |