SCHEMBL31000244

SCHEMBL31000244

COc1cc2ncc(I)n2nc1C1CC(F)(F)C1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TRPC6 Q9Y210 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24975688 0.85 PDE10A (0.34) TRPC6
SCHEMBL31000219 0.85 — —
SCHEMBL31000263 0.82 FYN (0.32) —
SCHEMBL31000128 0.78 IGF1R (0.32) —
SCHEMBL31000236 0.76 FYN (0.32) —
SCHEMBL31000216 0.76 PDE2A (0.36) —
SCHEMBL31000240 0.75 DYRK1A (0.39) —
SCHEMBL31000167 0.74 CHRM5 (0.33) TRPC6
SCHEMBL31000298 0.71 TYRO3 (0.33) —
SCHEMBL24975689 0.70 PDE10A (0.36) TRPC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4658659-A2 MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF Children's Hospital Medical Center (US) 2025-12-10 — — EP disclosed
WO-2024163764-A2 MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2024-08-08 — — WO disclosed
Send feedback