Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NRAS | P01111 | 2/20 | 0.34 |
| ▸ | FLT3 | P36888 | 2/20 | 0.34 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.31 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31000086 | 0.74 | CDK7 (0.41) | NRASFLT3 | |
| SCHEMBL31000126 | 0.71 | MKNK1 (0.34) | EIF2AK4 | |
| SCHEMBL31000157 | 0.71 | EIF2AK4 (0.34) | EIF2AK4 | |
| SCHEMBL31000211 | 0.69 | IGF1R (0.32) | NRASFLT3 | |
| SCHEMBL31000239 | 0.69 | EIF2AK4 (0.34) | EIF2AK4 | |
| SCHEMBL31000273 | 0.66 | EIF2AK4 (0.43) | NRASFLT3EIF2AK4MAP3K14 | |
| SCHEMBL31000269 | 0.64 | EIF2AK4 (0.43) | NRASFLT3EIF2AK4 | |
| SCHEMBL4426967 | 0.63 | CDK2 (0.38) | — | |
| SCHEMBL28705227 | 0.60 | PIK3CA (0.47) | NRASFLT3EIF2AK4MAP3K14 | |
| SCHEMBL29544366 | 0.60 | PIK3CA (0.47) | NRASFLT3EIF2AK4MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658659-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | Children's Hospital Medical Center (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163764-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2024-08-08 | — | — | WO | disclosed |