Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31000239 | 0.90 | EIF2AK4 (0.34) | EIF2AK4 | |
| SCHEMBL31341123 | 0.84 | GABRA1 (0.37) | EIF2AK4GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL31000273 | 0.82 | EIF2AK4 (0.43) | EIF2AK4 | |
| SCHEMBL30716641 | 0.78 | GABRA1 (0.39) | EIF2AK4GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL31000126 | 0.78 | MKNK1 (0.34) | EIF2AK4 | |
| SCHEMBL31000269 | 0.77 | EIF2AK4 (0.43) | EIF2AK4 | |
| SCHEMBL31000223 | 0.74 | FLT3 (0.37) | EIF2AK4 | |
| SCHEMBL24574150 | 0.72 | GABRA1 (0.48) | EIF2AK4GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL31068067 | 0.72 | GABRA1 (0.48) | EIF2AK4GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL31000145 | 0.71 | NRAS (0.34) | EIF2AK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658659-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | Children's Hospital Medical Center (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163764-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2024-08-08 | — | — | WO | disclosed |