Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 5/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.37 |
| ▸ | CDK9 | P50750 | 3/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | JUN | P05412 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31000196 | 0.88 | CFTR (0.39) | CFTRCCNT1CDK9IGF1RDNMT3A | |
| SCHEMBL31000115 | 0.88 | CFTR (0.40) | CFTRCCNT1CDK9IGF1RDNMT3A | |
| SCHEMBL31000195 | 0.87 | CFTR (0.36) | CFTRCCNT1CDK9IGF1RGPR119 | |
| SCHEMBL31000106 | 0.87 | CFTR (0.37) | CFTRCCNT1CDK9IGF1RDNMT3A | |
| SCHEMBL31000243 | 0.85 | CFTR (0.39) | CFTRCCNT1CDK9IGF1RPDE4B | |
| SCHEMBL30698310 | 0.84 | ALK (0.35) | CFTRCCNT1CDK9GPR119MALT1 | |
| SCHEMBL31000138 | 0.84 | PDE4D (0.37) | CFTRCCNT1CDK9KDM4EMEN1 | |
| SCHEMBL31000143 | 0.81 | FLT3 (0.41) | CCNT1CDK9CDK2MAPK8MAPK9 | |
| SCHEMBL30248495 | 0.80 | IGF1R (0.38) | CFTRCCNT1CDK9IGF1RDNMT3A | |
| SCHEMBL31000268 | 0.80 | USP30 (0.37) | CFTRCCNT1CDK9GPR119PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658659-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | Children's Hospital Medical Center (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163764-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2024-08-08 | — | — | WO | disclosed |