Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 4/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.30 |
| ▸ | ACVR2A | P27037 | 1/20 | 0.30 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24975688 | 0.88 | PDE10A (0.34) | FYNLRRK2 | |
| SCHEMBL31000244 | 0.82 | TRPC6 (0.31) | — | |
| SCHEMBL31000219 | 0.80 | — | — | |
| SCHEMBL31000211 | 0.76 | IGF1R (0.32) | FYNLRRK2 | |
| SCHEMBL31000185 | 0.75 | ACVR2A (0.32) | LRRK2ACVR2ATGFBR2 | |
| SCHEMBL31000324 | 0.74 | DYRK1A (0.40) | FYN | |
| SCHEMBL30698308 | 0.73 | NRAS (0.33) | FYNLRRK2 | |
| SCHEMBL31000193 | 0.73 | CHRM5 (0.34) | LRRK2ACVR2ATGFBR2 | |
| SCHEMBL31000298 | 0.73 | TYRO3 (0.33) | — | |
| SCHEMBL24975689 | 0.72 | PDE10A (0.36) | FYNLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658659-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | Children's Hospital Medical Center (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163764-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2024-08-08 | — | — | WO | disclosed |