Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | SUV39H2 | Q9H5I1 | 14/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31000313 | 0.84 | SUV39H2 (0.33) | CHRM5SUV39H2 | |
| SCHEMBL31000272 | 0.82 | PDE4B (0.34) | PDE4BCHRM5SUV39H2MEN1KMT2A | |
| SCHEMBL31000292 | 0.82 | PDE4B (0.39) | PDE4BCHRM5NPC1TLR9MEN1 | |
| SCHEMBL31639341 | 0.71 | PDE10A (0.34) | TLR9MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL30698334 | 0.69 | KDM4E (0.32) | NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL30632316 | 0.67 | JUND (0.34) | SUV39H2NPC1MEN1RAB9AKMT2A | |
| SCHEMBL31639231 | 0.66 | HPGD (0.34) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL31639301 | 0.65 | KDM4E (0.34) | PDE4BCHRM5SUV39H2MEN1KMT2A | |
| SCHEMBL31000261 | 0.65 | IGF1R (0.38) | — | |
| SCHEMBL31639289 | 0.64 | KDM4E (0.36) | TLR9MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658659-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | Children's Hospital Medical Center (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163764-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2024-08-08 | — | — | WO | disclosed |