Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 3/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 4/20 | 0.34 |
| ▸ | ECE1 | P42892 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3095525 | 0.95 | FOLH1 (0.39) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL3105990 | 0.85 | SIRT6 (0.35) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL2979463 | 0.85 | FOLH1 (0.42) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL2979464 | 0.85 | FOLH1 (0.42) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL2979466 | 0.85 | FOLH1 (0.42) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL3094807 | 0.81 | LMNA (0.38) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL3094812 | 0.81 | LMNA (0.38) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL3105775 | 0.81 | FPR2 (0.37) | MMP1MMP3MMP9FOLH1CYP1A2 | |
| SCHEMBL2987576 | 0.80 | FOLH1 (0.49) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL2987580 | 0.80 | FOLH1 (0.49) | LMNACYP3A4NFKB1BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |