SCHEMBL31005083

SCHEMBL31005083

Oc1ccccc1CC[C@H](O)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.48
RIPK1 Q13546 1/20 0.47
LMNA P02545 1/20 0.45
HSPA5 P11021 1/20 0.45
KDM4E B2RXH2 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
AKR1B1 P15121 1/20 0.44
MPO P05164 2/20 0.43
PPARG P37231 1/20 0.42
PPARA Q07869 1/20 0.42
AOC3 Q16853 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31005082 1.00 TAAR1 (0.48) TAAR1RIPK1LMNAHSPA5KDM4E
SCHEMBL11050916 1.00 TAAR1 (0.48) TAAR1RIPK1LMNAHSPA5KDM4E
SCHEMBL11741421 0.91 MPO (0.47) TAAR1RIPK1LMNAHSPA5KDM4E
SCHEMBL7809658 0.88 RIPK1 (0.53) RIPK1LMNAKDM4EL3MBTL1PPARG
SCHEMBL985017 0.84 TAAR1 (0.52) TAAR1HSPA5AKR1B1MPO
SCHEMBL11050132 0.82 AOC3 (0.46) KDM4EAOC3
SCHEMBL13976392 0.81 TAAR1 (0.58) TAAR1HSPA5AKR1B1MPO
SCHEMBL4397437 0.81 TAAR1 (0.48) TAAR1HSPA5AKR1B1MPO
SCHEMBL9387764 0.80 HTT (0.47) TAAR1RIPK1LMNA
SCHEMBL936320 0.79 PPARG (0.58) RIPK1LMNAKDM4EL3MBTL1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118307390-B Preparation method of chiral chroman precursor 南开大学 2024-08-23 CN disclosed
CN-118307390-A Preparation method of chiral chroman precursor 南开大学 2024-07-09 CN disclosed