Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 7/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | NPY4R | P50391 | 8/20 | 0.32 |
| ▸ | NPY1R | P25929 | 6/20 | 0.32 |
| ▸ | NPY2R | P49146 | 5/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3095595 | 0.90 | CA12 (0.36) | FPR2CA12CA1CA2CA9 | |
| SCHEMBL3109030 | 0.89 | CA12 (0.37) | FPR2CA12CA1CA2CA9 | |
| SCHEMBL3103245 | 0.87 | CA12 (0.38) | FPR2CA12CA1CA2CA9 | |
| SCHEMBL3097941 | 0.85 | CA12 (0.39) | FPR2CA12CA1CA2CA9 | |
| SCHEMBL3098146 | 0.84 | OTC (0.34) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL3105775 | 0.82 | FPR2 (0.37) | FPR2CA12CA1CA2CA9 | |
| SCHEMBL3091681 | 0.81 | FPR2 (0.36) | FPR2 | |
| SCHEMBL3097853 | 0.80 | C3AR1 (0.43) | FPR2CA12CA1CA2CA9 | |
| SCHEMBL3103384 | 0.79 | CA12 (0.39) | FPR2CA12CA1CA2CA9 | |
| SCHEMBL24293942 | 0.77 | NPY4R (0.35) | NPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |