Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | NPY4R | P50391 | 15/20 | 0.34 |
| ▸ | NPY1R | P25929 | 9/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.34 |
| ▸ | NPY2R | P49146 | 5/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3097941 | 0.96 | CA12 (0.39) | CA12CA1CA2CA9NPY4R | |
| SCHEMBL3095595 | 0.91 | CA12 (0.36) | CA12CA1CA2CA9NPY4R | |
| SCHEMBL3103384 | 0.90 | CA12 (0.39) | CA12CA1CA2CA9FPR2 | |
| SCHEMBL3100588 | 0.89 | FPR2 (0.35) | CA12CA1CA2CA9NPY4R | |
| SCHEMBL3103245 | 0.88 | CA12 (0.38) | CA12CA1CA2CA9FPR2 | |
| SCHEMBL3106289 | 0.86 | CA12 (0.41) | CA12CA1CA2CA9FPR2 | |
| SCHEMBL3099111 | 0.82 | CYP1A2 (0.33) | CA12CA1CA2CA9FPR2 | |
| SCHEMBL3095596 | 0.81 | CPB2 (0.36) | CA12CA1CA9FPR2 | |
| SCHEMBL3091575 | 0.81 | OTC (0.37) | CA12CA1CA2CA9NPY4R | |
| SCHEMBL2992625 | 0.81 | OTC (0.37) | CA12CA1CA2CA9NPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |